Anti-WDFY4 antibody (1-160) (STJ26942)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal WDFY4 (1-160) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | WDFY4 |
| Gene ID | 57705 |
| Uniprot ID | WDFY4_HUMAN |
| Immunogen Region | 1-160 |
| Immunogen Sequence | MEAEDLSKAEDRNEDPGSKN EGQLAAVQPDVPHGGQSSSP TALWDMLERKFLEYQQLTHK SPIERQKSLLSLLPLFLKAW EHSVGIICFPSLQRLAEDVS DQLAQQLQKALVGKPAEQAR LAAGQLLWWKGDVDQDGYLL LKSVYVLTGTDSETLGRVAE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human WDFY4 (NP_065996.1). |
Additional Info
| Function | Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Also plays a role in B-cell survival through regulation of autophagy. |
| Protein Name | Wd Repeat- And Fyve Domain-Containing Protein 4 |
| Database Links | |
| Cellular Localisation | Early EndosomeEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Wd Repeat- And Fyve Domain-Containing Protein 4 antibodyAnti-WDFY4 antibodyAnti-C10orf64 antibodyAnti-KIAA1607 antibody |
Information sourced from Uniprot.org