Anti-VSIR antibody (STJA0008319)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human VISTA
General Information
| Short Description | Rabbit polyclonal anti-V-type immunoglobulin domain-containing suppressor of T-cell activation for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VSIR |
| Gene ID | 64115 |
| Uniprot ID | VISTA_HUMAN |
| Immunogen | Synthesized peptide derived from human VISTA |
| Specificity | This antibody detects endogenous levels of VISTA at Human, Mouse |
Additional Info
| Post Translational Modifications | At the cell surface, may be cleaved by MMP14. N-glycosylated. |
| Function | Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation. |
| Protein Name | V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell ActivationPlatelet Receptor Gi24Stress-Induced Secreted Protein-1Sisp-1V-Set Domain-Containing Immunoregulatory ReceptorV-Set Immunoregulatory Receptor |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation antibodyAnti-Platelet Receptor Gi24 antibodyAnti-Stress-Induced Secreted Protein-1 antibodyAnti-Sisp-1 antibodyAnti-V-Set Domain-Containing Immunoregulatory Receptor antibodyAnti-V-Set Immunoregulatory Receptor antibodyAnti-VSIR antibodyAnti-C10orf54 antibodyAnti-SISP1 antibodyAnti-VISTA antibodyAnti-PP2135 antibodyAnti-UNQ730 antibodyAnti-PRO1412 antibody |
Information sourced from Uniprot.org