| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-VPS37C (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.03-0.1µg/mlIHC-3.75µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
VPS37C |
| Gene ID: |
55048 |
| Uniprot ID: |
VP37C_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_060436.4 |
| Immunogen Sequence: |
ETLKDKTLQELEELQ |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37cHvps37cEscrt-I Complex Subunit Vps37c |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinProbably Associates With MembranesRecruited To The Plasma Membrane By Hiv-1 |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37c antibodyAnti-Hvps37c antibodyAnti-Escrt-I Complex Subunit Vps37c antibodyAnti-VPS37C antibodyAnti-PML39 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
