Anti-VPS37A antibody (224-397) (STJ110163)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal VPS37A (224-397) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VPS37A |
| Gene ID | 137492 |
| Uniprot ID | VP37A_HUMAN |
| Immunogen Region | 224-397 |
| Immunogen Sequence | MPDVPDAFPELSELSVSQLT DMNEQEEVLLEQFLTLPQLK QIITDKDDLVKSIEELARKN LLLEPSLEAKRQTVLDKYEL LTQMKSTFEKKMQRQHELSE SCSASALQARLKVAAHEAEE ESDNIAEDFLEGKMEIDDFL SSFMEKRTICHCRRAKEEKL QQAIAMHSQFHAPL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2). |
Additional Info
| Tissue Specificity | Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37aHvps37aEscrt-I Complex Subunit Vps37aHepatocellular Carcinoma-Related Protein 1 |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinNucleus |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37a antibodyAnti-Hvps37a antibodyAnti-Escrt-I Complex Subunit Vps37a antibodyAnti-Hepatocellular Carcinoma-Related Protein 1 antibodyAnti-VPS37A antibodyAnti-HCRP1 antibody |
Information sourced from Uniprot.org