Anti-VPS13C antibody (STJA0009392)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human VPS13C
General Information
| Short Description | Rabbit polyclonal anti-Intermembrane lipid transfer protein VPS13C for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VPS13C |
| Gene ID | 54832 |
| Uniprot ID | VP13C_HUMAN |
| Immunogen | Synthesized peptide derived from human VPS13C |
| Specificity | This antibody detects endogenous levels of VPS13C at Human, Mouse |
Additional Info
| Function | Mediates the transfer of lipids between membranes at organelle contact sites. Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. |
| Protein Name | Intermembrane Lipid Transfer Protein Vps13cVacuolar Protein Sorting-Associated Protein 13c |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembraneLipid DropletEndoplasmic Reticulum MembraneLysosome MembraneLate Endosome MembraneMay Localize To Endoplasmic Reticulum-Endolysosome Contact Sites |
| Alternative Antibody Names | Anti-Intermembrane Lipid Transfer Protein Vps13c antibodyAnti-Vacuolar Protein Sorting-Associated Protein 13c antibodyAnti-VPS13C antibodyAnti-KIAA1421 antibody |
Information sourced from Uniprot.org