Anti-VPS13A antibody (STJA0009246)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human VPS13A
General Information
| Short Description | Rabbit polyclonal anti-Intermembrane lipid transfer protein VPS13A for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VPS13A |
| Gene ID | 23230 |
| Uniprot ID | VP13A_HUMAN |
| Immunogen | Synthesized peptide derived from human VPS13A |
| Specificity | This antibody detects endogenous levels of VPS13A at Human, Mouse |
Additional Info
| Function | Mediates the transfer of lipids between membranes at organelle contact sites. Binds phospholipids. Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria. Negatively regulates lipid droplet size and motility. Required for efficient lysosomal protein degradation. |
| Protein Name | Intermembrane Lipid Transfer Protein Vps13aChorea-Acanthocytosis ProteinChoreinVacuolar Protein Sorting-Associated Protein 13a |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneEndosome MembraneLysosome MembraneLipid DropletGolgi ApparatusCytoplasmic VesicleSecretory VesicleNeuronal Dense Core VesicleLocalizes At Mitochondria-Endosomes And Mitochondria-Endoplasmic Reticulum Contact Sites |
| Alternative Antibody Names | Anti-Intermembrane Lipid Transfer Protein Vps13a antibodyAnti-Chorea-Acanthocytosis Protein antibodyAnti-Chorein antibodyAnti-Vacuolar Protein Sorting-Associated Protein 13a antibodyAnti-VPS13A antibodyAnti-CHAC antibodyAnti-KIAA0986 antibody |
Information sourced from Uniprot.org