![Anti-von Willebrand Factor antibody [36B11] (STJ16101802)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152308/347155/STJ16101802_1__59046.1681999430.jpg?c=1 "Anti-von Willebrand Factor antibody [36B11] (STJ16101802)")
![Anti-von Willebrand Factor antibody [36B11] (STJ16101802)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152308/347155/STJ16101802_1__59046.1681999430.jpg?c=1 "Anti-von Willebrand Factor antibody [36B11] (STJ16101802)")
Anti-von Willebrand Factor antibody [36B11] (STJ16101802)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenProkaryotic recombinant fusion protein corresponding to the A2 domain of the von Willebrand molecule.
General Information
| Short Description | Mouse monoclonal anti-von Willebrand Factor for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 36B11 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | >=21 mg/L |
| Dilution Range | IHC-P 1:200 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | VWF |
| Gene ID | 7450 |
| Uniprot ID | VWF_HUMAN |
| Immunogen | Prokaryotic recombinant fusion protein corresponding to the A2 domain of the von Willebrand molecule. |
Additional Info
| Tissue Specificity | Plasma. |
| Post Translational Modifications | All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated. |
| Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
| Protein Name | Von Willebrand FactorVwf Cleaved Into - Von Willebrand Antigen 2Von Willebrand Antigen Ii |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140837Reactome: R-HSA-216083Reactome: R-HSA-354192Reactome: R-HSA-354194Reactome: R-HSA-372708Reactome: R-HSA-430116Reactome: R-HSA-5674135Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9649948Reactome: R-HSA-9656223Reactome: R-HSA-9672391Reactome: R-HSA-9672393Reactome: R-HSA-9845619Reactome: R-HSA-9845620Reactome: R-HSA-9845621Reactome: R-HSA-9845622Reactome: R-HSA-9846298 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalized To Storage Granules |
| Alternative Antibody Names | Anti-Von Willebrand Factor antibodyAnti-Vwf Cleaved Into - Von Willebrand Antigen 2 antibodyAnti-Von Willebrand Antigen Ii antibodyAnti-VWF antibodyAnti-F8VWF antibody |
Information sourced from Uniprot.org