• STJ72161 (2µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-VLCAD antibody (N-Term) (STJ72161)

SKU:
STJ72161-100

Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-VLCAD (N-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:2000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ACADVL
Gene ID: 37
Uniprot ID: ACADV_HUMAN
Immunogen Region: N-Term
Accession Number: NP_000009.1; NP_001029031.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_000009.1; NP_001029031.1).
Immunogen Sequence: DKSDSHPSDALTRK
Post Translational Modifications S-nitrosylation at Cys-237 in liver improves catalytic efficiency.
Function Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains.
Protein Name Very Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial
Vlcad
Database Links Reactome: R-HSA-381038
Reactome: R-HSA-77305
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Isoform 2: Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Very Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody
Anti-Vlcad antibody
Anti-ACADVL antibody
Anti-VLCAD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance