Anti-VEGF-D antibody (200-300) [S4MR] (STJ11102974)

Name: Anti-VEGF-D antibody (200-300) [S4MR] (STJ11102974)
SKU: STJ11102974
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102974

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit monoclonal VEGF-D (200-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S4MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	VEGFD
Gene ID	2277
Uniprot ID	VEGFD_HUMAN
Immunogen Region	200-300
Immunogen Sequence	YSIIRRSIQIPEEDRCSHSK KLCPIDMLWDSNKCKCVLQE ENPLAGTEDHSHLQEPALCG PHMMFDEDRCECVCKTPCPK DLIQHPKNCSCFECKESLET C
Specificity	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human VEGF-D (O43915).

Tissue Specificity	Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
Post Translational Modifications	Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
Function	Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Protein Name	Vascular Endothelial Growth Factor D Vegf-D C-Fos-Induced Growth Factor Figf
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-194313 Reactome: R-HSA-195399
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Vascular Endothelial Growth Factor D antibody Anti-Vegf-D antibody Anti-C-Fos-Induced Growth Factor antibody Anti-Figf antibody Anti-VEGFD antibody Anti-FIGF antibody

Information sourced from Uniprot.org