Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-VDAC3 antibody (STJ191627)

SKU:
STJ191627
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Voltage-dependent anion-selective channel protein 3 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VDAC3
Gene ID: 7419
Uniprot ID: VDAC3_HUMAN
Specificity: VDAC3 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Function Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations. Involved in male fertility and sperm mitochondrial sheath formation.
Protein Name Non-Selective Voltage-Gated Ion Channel Vdac3
Vdac-3
Hvdac3
Outer Mitochondrial Membrane Protein Porin 3
Database Links Reactome: R-HSA-5205685
Reactome: R-HSA-5689880
Reactome: R-HSA-8949215
Cellular Localisation Mitochondrion Outer Membrane
Membrane
May Localize To Non-Mitochondrial Membranes
Alternative Antibody Names Anti-Non-Selective Voltage-Gated Ion Channel Vdac3 antibody
Anti-Vdac-3 antibody
Anti-Hvdac3 antibody
Anti-Outer Mitochondrial Membrane Protein Porin 3 antibody
Anti-VDAC3 antibody

Information sourced from Uniprot.org

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