Anti-VAV2 antibody [R06-8F5] (STJA0035402)

Name: Anti-VAV2 antibody [R06-8F5] (STJA0035402)
SKU: STJA0035402
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenA synthetic peptide of human VAV2

STJA0035402

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Short Description	Rabbit monoclonal anti-VAV2 for use in WB, ICC, IF and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ICC/IF/IP
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	R06-8F5
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.3 mg/mL
Purification	Affinity Purified
Dilution Range	WB 1:500-1:1000 IF 1:50-1:200 IP 1:20
Formulation	50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction	Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Gene Symbol	VAV2
Gene ID	7410
Uniprot ID	VAV2_HUMAN
Immunogen	A synthetic peptide of human VAV2

Tissue Specificity	Widely expressed.
Post Translational Modifications	Phosphorylated on tyrosine residues in response to FGR activation.
Function	Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
Protein Name	Guanine Nucleotide Exchange Factor Vav2 Vav-2
Database Links	Reactome: R-HSA-114604 Reactome: R-HSA-193648 Reactome: R-HSA-2029482 Reactome: R-HSA-2424491 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-3928665 Reactome: R-HSA-416482 Reactome: R-HSA-4420097 Reactome: R-HSA-445144 Reactome: R-HSA-5218920 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 Reactome: R-HSA-9664422 Reactome: R-HSA-9748787
Cellular Localisation
Alternative Antibody Names	Anti-Guanine Nucleotide Exchange Factor Vav2 antibody Anti-Vav-2 antibody Anti-VAV2 antibody

Information sourced from Uniprot.org