• Western blot analysis of lysates from Jurkat cells, using VAV1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Vav1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-VAV1 antibody (141-190 aa) (STJ96228)

SKU:
STJ96228

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Proto-oncogene vav (141-190 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VAV1
Gene ID: 7409
Uniprot ID: VAV_HUMAN
Immunogen Region: 141-190 aa
Specificity: Vav1 Polyclonal Antibody detects endogenous levels of Vav1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human VAV1 at the amino acid range 141-190
Post Translational Modifications Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.
Function Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Protein Name Proto-Oncogene Vav
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1257604
Reactome: R-HSA-1433557
Reactome: R-HSA-193648
Reactome: R-HSA-2029482
Reactome: R-HSA-2219530
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-389359
Reactome: R-HSA-416482
Reactome: R-HSA-4420097
Reactome: R-HSA-512988
Reactome: R-HSA-5218920
Reactome: R-HSA-6811558
Reactome: R-HSA-8980692
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-9027284
Reactome: R-HSA-912631
Reactome: R-HSA-9664422
Reactome: R-HSA-9679191
Reactome: R-HSA-9748787
Reactome: R-HSA-983695
Alternative Antibody Names Anti-Proto-Oncogene Vav antibody
Anti-VAV1 antibody
Anti-VAV antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance