| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Proto-oncogene vav (131-180 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VAV1 |
| Gene ID: | 7409 |
| Uniprot ID: | VAV_HUMAN |
| Immunogen Region: | 131-180 aa |
| Specificity: | VAV1 Polyclonal Antibody detects endogenous levels of VAV1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human VAV1 at the amino acid range 131-180 |
| Post Translational Modifications | Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN. |
| Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
| Protein Name | Proto-Oncogene Vav |
| Database Links | Reactome: R-HSA-114604 Reactome: R-HSA-1257604 Reactome: R-HSA-1433557 Reactome: R-HSA-193648 Reactome: R-HSA-2029482 Reactome: R-HSA-2219530 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-389359 Reactome: R-HSA-416482 Reactome: R-HSA-4420097 Reactome: R-HSA-512988 Reactome: R-HSA-5218920 Reactome: R-HSA-6811558 Reactome: R-HSA-8980692 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9027284 Reactome: R-HSA-912631 Reactome: R-HSA-9664422 Reactome: R-HSA-9679191 Reactome: R-HSA-9748787 Reactome: R-HSA-983695 |
| Alternative Antibody Names | Anti-Proto-Oncogene Vav antibody Anti-VAV1 antibody Anti-VAV antibody |
Information sourced from Uniprot.org