Anti-VASH2 antibody (STJA0004558)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFull length fusion protein
General Information
| Short Description | Rabbit polyclonal anti-Tubulinyl-Tyr Carboxypeptidase 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-2000 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | VASH2 |
| Gene ID | 79805 |
| Uniprot ID | VASH2_HUMAN |
| Immunogen | Full length fusion protein |
Additional Info
| Function | Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation. |
| Protein Name | Tubulinyl-Tyr Carboxypeptidase 2Vasohibin-2Vasohibin-Like Protein |
| Database Links | Reactome: R-HSA-8955332 |
| Cellular Localisation | CytoplasmSecretedCytoskeletonMainly Localizes In The CytoplasmSome Fraction Is Secreted Via A Non-Canonical Secretion SystemInteraction With Svbp Promotes SecretionAssociates With Microtubules |
| Alternative Antibody Names | Anti-Tubulinyl-Tyr Carboxypeptidase 2 antibodyAnti-Vasohibin-2 antibodyAnti-Vasohibin-Like Protein antibodyAnti-VASH2 antibodyAnti-VASHL antibody |
Information sourced from Uniprot.org