Anti-VAP-1/AOC3 antibody [TK8-14] (STJA0019247)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Amine Oxidase Copper-Containing 3 antibody for use in ELISA, FC, IF, IHC, IP and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/IF/IHC/IP/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | TK8-14 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | AOC3 |
| Gene ID | 8639 |
| Uniprot ID | AOC3_HUMAN |
Additional Info
| Post Translational Modifications | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. N- and O-glycosylated. |
| Function | Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Isoform 2: Has no semicarbazide-sensitive amine oxidase (SSAO) activity. |
| Protein Name | Amine Oxidase Copper-Containing 3Amine Oxidase Copper-Containing 3Copper Amine OxidaseHpaoSemicarbazide-Sensitive Amine OxidaseSsaoVascular Adhesion Protein 1Vap-1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Amine Oxidase Copper-Containing 3 antibodyAnti-Amine Oxidase Copper-Containing 3 antibodyAnti-Copper Amine Oxidase antibodyAnti-Hpao antibodyAnti-Semicarbazide-Sensitive Amine Oxidase antibodyAnti-Ssao antibodyAnti-Vascular Adhesion Protein 1 antibodyAnti-Vap-1 antibodyAnti-AOC3 antibodyAnti-VAP1 antibody |
Information sourced from Uniprot.org