Anti-VAMP4 antibody (STJA0010283)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human VAMP4
STJA0010283
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General Information

Short DescriptionRabbit polyclonal anti-Vesicle-associated membrane protein 4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolVAMP4
Gene ID8674
Uniprot IDVAMP4_HUMAN
ImmunogenSynthesized peptide derived from human VAMP4
SpecificityThis antibody detects endogenous levels of VAMP4 at Human, Mouse, Rat

Additional Info

Function Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
Protein Name Vesicle-Associated Membrane Protein 4
Vamp-4
Database Links Reactome: R-HSA-6811440
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Single-Pass Type Iv Membrane Protein
Associated With Trans Golgi Network (Tgn) And Newly Formed Immature Secretory Granules (Isg)
Not Found On The Mature Secretory Organelles
Alternative Antibody Names Anti-Vesicle-Associated Membrane Protein 4 antibody
Anti-Vamp-4 antibody
Anti-VAMP4 antibody

Information sourced from Uniprot.org

Citations

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