| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VAMP4 (1-115) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VAMP4 |
| Gene ID: |
8674 |
| Uniprot ID: |
VAMP4_HUMAN |
| Immunogen Region: |
1-115 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human VAMP4 (NP_003753.2). |
| Immunogen Sequence: |
MPPKFKRHLNDDDVTGSVKS ERRNLLEDDSDEEEDFFLRG PSGPRFGPRNDKIKHVQNQV DEVIDVMQENITKVIERGER LDELQDKSESLSDNATAFSN RSKQLRRQMWWRGCK |
| Function | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. |
| Protein Name | Vesicle-Associated Membrane Protein 4Vamp-4 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Iv Membrane ProteinAssociated With Trans Golgi Network (Tgn) And Newly Formed Immature Secretory Granules (Isg)Not Found On The Mature Secretory Organelles |
| Alternative Antibody Names | Anti-Vesicle-Associated Membrane Protein 4 antibodyAnti-Vamp-4 antibodyAnti-VAMP4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
