| Short Description : | Rabbit polyclonal VAMP4 (1-115) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VAMP4 |
| Gene ID: | 8674 |
| Uniprot ID: | VAMP4_HUMAN |
| Immunogen Region: | 1-115 |
| Immunogen Sequence: | MPPKFKRHLNDDDVTGSVKS ERRNLLEDDSDEEEDFFLRG PSGPRFGPRNDKIKHVQNQV DEVIDVMQENITKVIERGER LDELQDKSESLSDNATAFSN RSKQLRRQMWWRGCK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human VAMP4 (NP_003753.2). |
| Function | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. |
| Protein Name | Vesicle-Associated Membrane Protein 4Vamp-4 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Iv Membrane ProteinAssociated With Trans Golgi Network (Tgn) And Newly Formed Immature Secretory Granules (Isg)Not Found On The Mature Secretory Organelles |
| Alternative Antibody Names | Anti-Vesicle-Associated Membrane Protein 4 antibodyAnti-Vamp-4 antibodyAnti-VAMP4 antibody |
Information sourced from Uniprot.org
