| Short Description : | Rabbit polyclonal anti-VAMP 1 (2-35) for use in IHC and WB in Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Vamp1 |
| Gene ID: | 22317 |
| Uniprot ID: | VAMP1_MOUSE |
| Immunogen: | A synthetic peptide from aa region 2-35 of mouse VAMP-1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region: | 2-35 |
| Specificity: | Specific for VAMP1. |
| Post Translational Modifications | (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type X (BoNT/X) which hydrolyzes the 68-Arg-|-Ala-69 bond and probably inhibits neurotransmitter release. It remains unknown whether BoNT/X is ever produced, or what organisms it targets. |
| Function | Involved in the targeting and/or fusion of transport vesicles to their target membrane. |
| Protein Name | Vesicle-Associated Membrane Protein 1Vamp-1Synaptobrevin-1 |
| Database Links | |
| Cellular Localisation | Isoform 1: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Type Iv Membrane ProteinSynapseSynaptosomeIsoform 2: Cytoplasmic Vesicle Membrane |
| Alternative Antibody Names | Anti-Vesicle-Associated Membrane Protein 1 antibodyAnti-Vamp-1 antibodyAnti-Synaptobrevin-1 antibodyAnti-Vamp1 antibodyAnti-Syb1 antibody |
Information sourced from Uniprot.org
