Anti-VAChT antibody (STJ16102841)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ImmunogenSynthetic peptide from the C-terminus of human VAChT (11 amino acid residues) conjugated to BSA
General Information
| Short Description | Rabbit polyclonal anti-VAChT for use in IHC-F in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Dilution Range | IHCF 1:800-1:1, 200 |
| Formulation | Lyophilized; reconstitute in 100 ยตl dist. water |
| Storage Instruction | Store at 2-8ยฐC for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | SLC18A3 |
| Gene ID | 6572 |
| Uniprot ID | VACHT_HUMAN |
| Immunogen | Synthetic peptide from the C-terminus of human VAChT (11 amino acid residues) conjugated to BSA |
Additional Info
| Function | Electrogenic antiporter that exchanges one cholinergic neurotransmitter, acetylcholine or choline, with two intravesicular protons across the membrane of synaptic vesicles. Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to store neurotransmitters inside the vesicles prior to their release via exocytosis. Determines cholinergic vesicular quantal size at presynaptic nerve terminals in developing neuro-muscular junctions with an impact on motor neuron differentiation and innervation pattern. Part of forebrain cholinergic system, regulates hippocampal synapse transmissions that underlie spatial memory formation. Can transport serotonin. |
| Protein Name | Vesicular Acetylcholine TransporterVachtSolute Carrier Family 18 Member 3 |
| Database Links | Reactome: R-HSA-264642Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vesicular Acetylcholine Transporter antibodyAnti-Vacht antibodyAnti-Solute Carrier Family 18 Member 3 antibodyAnti-SLC18A3 antibodyAnti-VACHT antibody |
Information sourced from Uniprot.org