Anti-UTP18 antibody (70-260) (STJ117636)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UTP18 (70-260) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UTP18 |
| Gene ID | 51096 |
| Uniprot ID | UTP18_HUMAN |
| Immunogen Region | 70-260 |
| Immunogen Sequence | RRLRQRNRLRLEEDKPAVER CLEELVFGDVENDEDALLRR LRGPRVQEHEDSGDSEVENE AKGNFPPQKKPVWVDEEDED EEMVDMMNNRFRKDMMKNAS ESKLSKDNLKKRLKEEFQHA MGGVPAWAETTKRKTSSDDE SEEDEDDLLQRTGNFISTST SLPRGILKMKNCQHANAERP TVARISSVQFH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human UTP18 (NP_057085.2). |
Additional Info
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. |
| Protein Name | U3 Small Nucleolar Rna-Associated Protein 18 HomologWd Repeat-Containing Protein 50 |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-U3 Small Nucleolar Rna-Associated Protein 18 Homolog antibodyAnti-Wd Repeat-Containing Protein 50 antibodyAnti-UTP18 antibodyAnti-WDR50 antibodyAnti-CDABP0061 antibodyAnti-CGI-48 antibody |
Information sourced from Uniprot.org