Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-USP48 (1-300) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
USP48 |
Gene ID: |
84196 |
Uniprot ID: |
UBP48_HUMAN |
Immunogen Region: |
1-300 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human USP48 (NP_115612.4). |
Immunogen Sequence: |
MAPRLQLEKAAWRWAETVRP EEVSQEHIETAYRIWLEPCI RGVCRRNCKGNPNCLVGIGE HIWLGEIDENSFHNIDDPNC ERRKKNSFVGLTNLGATCYV NTFLQVWFLNLELRQALYLC PSTCSDYMLGDGIQEEKDYE PQTICEHLQYLFALLQNSNR RYIDPSGFVKALGLDTGQQQ DAQEFSKLFMSLLEDTLSKQ KNPDVRNIVQQQFCGEYAYV TVCNQCGRESKLLSKFYEL |
Tissue Specificity | Widely expressed. Expressed in the fetal inner ear. |
Function | Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. |
Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 48Deubiquitinating Enzyme 48Ubiquitin Thioesterase 48Ubiquitin-Specific Peptidase 48Ubiquitin-Specific Protease 48Ubiquitin-Specific-Processing Protease 48 |
Database Links | Reactome: R-HSA-5689880 |
Cellular Localisation | CytoplasmNucleus |
Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 48 antibodyAnti-Deubiquitinating Enzyme 48 antibodyAnti-Ubiquitin Thioesterase 48 antibodyAnti-Ubiquitin-Specific Peptidase 48 antibodyAnti-Ubiquitin-Specific Protease 48 antibodyAnti-Ubiquitin-Specific-Processing Protease 48 antibodyAnti-USP48 antibodyAnti-USP31 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance