Anti-USP47 antibody (1128-1287) (STJ117656)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal USP47 (1128-1287) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP47 |
| Gene ID | 55031 |
| Uniprot ID | UBP47_HUMAN |
| Immunogen Region | 1128-1287 |
| Immunogen Sequence | VEKMKSMSQLAVLSRRWKPS EMKLDPFQEVVLESSSVDEL REKLSEISGIPLDDIEFAKG RGTFPCDISVLDIHQDLDWN PKVSTLNVWPLYICDDGAVI FYRDKTEELMELTDEQRNEL MKKESSRLQKTGHRVTYSPR KEKALKIYLDGAPNKDLTQD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1128-1287 of human USP47 (NP_060414.3). |
Additional Info
| Tissue Specificity | Expressed in skeletal muscle, heart and testis. |
| Function | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 47Deubiquitinating Enzyme 47Ubiquitin Thioesterase 47Ubiquitin-Specific-Processing Protease 47 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 47 antibodyAnti-Deubiquitinating Enzyme 47 antibodyAnti-Ubiquitin Thioesterase 47 antibodyAnti-Ubiquitin-Specific-Processing Protease 47 antibodyAnti-USP47 antibody |
Information sourced from Uniprot.org