Anti-USP46 antibody (STJ191579)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin carboxyl-terminal hydrolase 46 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP46 |
| Gene ID | 64854 |
| Uniprot ID | UBP46_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | UBP46 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 46Deubiquitinating Enzyme 46Ubiquitin Thioesterase 46Ubiquitin-Specific-Processing Protease 46 |
| Database Links | |
| Cellular Localisation | CytoplasmUsp46/Wdr48/Wdr20 Complex Is Predominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 46 antibodyAnti-Deubiquitinating Enzyme 46 antibodyAnti-Ubiquitin Thioesterase 46 antibodyAnti-Ubiquitin-Specific-Processing Protease 46 antibodyAnti-USP46 antibody |
Information sourced from Uniprot.org