Anti-USP26 antibody (664-913) (STJ110306)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal USP26 (664-913) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP26 |
| Gene ID | 83844 |
| Uniprot ID | UBP26_HUMAN |
| Immunogen Region | 664-913 |
| Immunogen Sequence | TSLCQFHKAGGKPASSPGTP LSKVDFQTVPENPKRKKYVK TSKFVAFDRIINPTKDLYED KNIRIPERFQKVSEQTQQCD GMRICEQAPQQALPQSFPKP GTQGHTKNLLRPTKLNLQKS NRNSLLALGSNKNPRNKDIL DKIKSKAKETKRNDDKGDHT YRLISVVSHLGKTLKSGHYI CDAYDFEKQIWFTYDDMRVL GIQEAQMQEDRRCTGYIFFY MHNEIFEEMLKREENAQLN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 664-913 of human USP26 (NP_114113.1). |
Additional Info
| Tissue Specificity | Expressed in testis. |
| Function | Deubiquitinase regulating several biological processes through the deubiquitination of components of these processes. Involved in somatic cell reprogramming through the 'Lys-48'-linked deubiquitination and stabilization of CBX4 and CBX6, two components of the polycomb-repressive complex 1 (PRC1). Also deubiquitinates and probably stabilizes the androgen receptor (AR), regulating the androgen receptor signaling pathway. May play a role in spermatogenesis. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 26Deubiquitinating Enzyme 26Ubiquitin Thioesterase 26Ubiquitin-Specific-Processing Protease 26 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 26 antibodyAnti-Deubiquitinating Enzyme 26 antibodyAnti-Ubiquitin Thioesterase 26 antibodyAnti-Ubiquitin-Specific-Processing Protease 26 antibodyAnti-USP26 antibody |
Information sourced from Uniprot.org