Anti-USO1 antibody (663-962) (STJ118519)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal USO1 (663-962) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USO1 |
| Gene ID | 8615 |
| Uniprot ID | USO1_HUMAN |
| Immunogen Region | 663-962 |
| Immunogen Sequence | DLQLEELRQQVSTLKCQNEQ LQTAVTQQVSQIQQHKDQYN LLKIQLGKDNQHQGSYSEGA QMNGIQPEEIGRLREEIEEL KRNQELLQSQLTEKDSMIEN MKSSQTSGTNEQSSAIVSAR DSEQVAELKQELATLKSQLN SQSVEITKLQTEKQELLQKT EAFAKSVEVQGETETIIATK TTDVEGRLSALLQETKELKN EIKALSEERTAIKEQLDSSN STIAILQTEKDKLELEITD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 663-962 of human USO1 (NP_003706.2). |
Additional Info
| Post Translational Modifications | Phosphorylated in a cell cycle-specific manner.phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane.phosphorylation promotes dissociation. |
| Function | General vesicular transport factor required for intercisternal transport in the Golgi stack.it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. |
| Protein Name | General Vesicular Transport Factor P115Protein Uso1 HomologTranscytosis-Associated ProteinTapVesicle-Docking Protein |
| Database Links | Reactome: R-HSA-162658Reactome: R-HSA-204005Reactome: R-HSA-6807878 |
| Cellular Localisation | CytoplasmCytosolGolgi Apparatus MembranePeripheral Membrane ProteinRecycles Between The Cytosol And The Golgi Apparatus During InterphaseDuring InterphaseThe Phosphorylated Form Is Found Exclusively In CytosolThe Unphosphorylated Form Is Associated With Golgi Apparatus Membranes |
| Alternative Antibody Names | Anti-General Vesicular Transport Factor P115 antibodyAnti-Protein Uso1 Homolog antibodyAnti-Transcytosis-Associated Protein antibodyAnti-Tap antibodyAnti-Vesicle-Docking Protein antibodyAnti-USO1 antibodyAnti-VDP antibody |
Information sourced from Uniprot.org