| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-URP2/kindlin-3 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
FERMT3 |
| Gene ID: |
83706 |
| Uniprot ID: |
URP2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_113659.3; NP_848537.1 |
| Specificity: |
This antibody is expected to recognize both isoforms (NP_113659.3, NP_848537.1). |
| Immunogen Sequence: |
ERARGEELDED |
| Function | Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis. |
| Protein Name | Fermitin Family Homolog 3Kindlin-3Mig2-Like ProteinUnc-112-Related Protein 2 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Cell ProjectionPodosomePresent In The F-Actin Surrounding Ring Structure Of PodosomesWhich Are Specialized Adhesion Structures Of Hematopoietic Cells |
| Alternative Antibody Names | Anti-Fermitin Family Homolog 3 antibodyAnti-Kindlin-3 antibodyAnti-Mig2-Like Protein antibodyAnti-Unc-112-Related Protein 2 antibodyAnti-FERMT3 antibodyAnti-KIND3 antibodyAnti-MIG2B antibodyAnti-URP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
