Anti-Uroplakin II antibody (36-51aa) [ZR477] (STJ180689)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein
General Information
| Short Description | Rabbit monoclonal Uroplakin II (36-51aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR477 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | UPK3A |
| Gene ID | 7380 |
| Uniprot ID | UPK3A_HUMAN |
| Immunogen | Recombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein |
| Immunogen Region | 36-51aa |
| Specificity | Positive Control: Urothelial carcinoma |
Additional Info
| Tissue Specificity | Expressed in ureter. |
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. |
| Protein Name | Uroplakin-3aUp3aUroplakin IiiUpiii |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinHeterodimer Formation With Upk1b Is A Prerequisite To Exit Out Of The Endoplasmic Reticulum (Er) |
| Alternative Antibody Names | Anti-Uroplakin-3a antibodyAnti-Up3a antibodyAnti-Uroplakin Iii antibodyAnti-Upiii antibodyAnti-UPK3A antibodyAnti-UPK3 antibody |
Information sourced from Uniprot.org