| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Uroplakin (114-173aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZM204 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2b/Kappa + IgG1/Kappa |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100-200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
UPK1B |
| Gene ID: |
7348 |
| Uniprot ID: |
UPK1B_HUMAN |
| Immunogen Region: |
114-173aa |
| Specificity: |
Positive control: Bladder or urothelial carcinoma |
| Immunogen: |
Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein; recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) |
| Tissue Specificity | Bladder epithelium. |
| Post Translational Modifications | N-glycosylated with high-mannose oligosaccharides. |
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. |
| Protein Name | Uroplakin-1bUp1bTetraspanin-20Tspan-20Uroplakin IbUpib |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Uroplakin-1b antibodyAnti-Up1b antibodyAnti-Tetraspanin-20 antibodyAnti-Tspan-20 antibodyAnti-Uroplakin Ib antibodyAnti-Upib antibodyAnti-UPK1B antibodyAnti-TSPAN20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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