Anti-UQCC3 antibody (STJA0008434)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C11orf83
General Information
| Short Description | Rabbit polyclonal anti-Ubiquinol-cytochrome-c reductase complex assembly factor 3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UQCC3 |
| Gene ID | 790955 |
| Uniprot ID | UQCC3_HUMAN |
| Immunogen | Synthesized peptide derived from human C11orf83 |
| Specificity | This antibody detects endogenous levels of C11orf83 at Human, Mouse, Rat |
Additional Info
| Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology. |
| Protein Name | Ubiquinol-Cytochrome-C Reductase Complex Assembly Factor 3Assembly Factor Cbp4 Homolog |
| Database Links | Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ubiquinol-Cytochrome-C Reductase Complex Assembly Factor 3 antibodyAnti-Assembly Factor Cbp4 Homolog antibodyAnti-UQCC3 antibodyAnti-C11orf83 antibodyAnti-UNQ655 antibodyAnti-PRO1286 antibody |
Information sourced from Uniprot.org