Anti-UPK3B antibody (60-200) (STJ11104725)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Uroplakin-3b (60-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UPK3B |
| Gene ID | 105375355 |
| Uniprot ID | UPK3B_HUMAN |
| Immunogen Region | 60-200 |
| Immunogen Sequence | RLGEAAPGTPTPVSVAHLLS PVATELVPYTPQITAWDLEG KVTATTFSLEQPRCVFDGLA SASDTVWLVVAFSNASRGFQ NPETLADIPASPQLLTDGHY MTLPLSPDQLPCGDPMAGSG GAPVLRVGHDHGCHQQPFCN A |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human UPK3B (NP_085047.1). |
Additional Info
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. |
| Protein Name | Uroplakin-3bUp3bUroplakin IiibUpiiibP35 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinHeterodimer Formation With Upk1b Is A Prerequisite To Exit Out Of The Endoplasmic Reticulum (Er) |
| Alternative Antibody Names | Anti-Uroplakin-3b antibodyAnti-Up3b antibodyAnti-Uroplakin Iiib antibodyAnti-Upiiib antibodyAnti-P35 antibodyAnti-UPK3B antibody |
Information sourced from Uniprot.org