Anti-UPK3A antibody (19-207) (STJ112074)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UPK3A (19-207) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UPK3A |
| Gene ID | 7380 |
| Uniprot ID | UPK3A_HUMAN |
| Immunogen Region | 19-207 |
| Immunogen Sequence | VNLQPQLASVTFATNNPTLT TVALEKPLCMFDSKEALTGT HEVYLYVLVDSAISRNASVQ DSTNTPLGSTFLQTEGGRTG PYKAVAFDLIPCSDLPSLDA IGDVSKASQILNAYLVRVGA NGTCLWDPNFQGLCNAPLSA ATEYRFKYVLVNMSTGLVED QTLWSDPIRTNQLTPYSTID TWPGRRSGG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 19-207 of human UPK3A (NP_008884.1). |
Additional Info
| Tissue Specificity | Expressed in ureter. |
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. |
| Protein Name | Uroplakin-3aUp3aUroplakin IiiUpiii |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinHeterodimer Formation With Upk1b Is A Prerequisite To Exit Out Of The Endoplasmic Reticulum (Er) |
| Alternative Antibody Names | Anti-Uroplakin-3a antibodyAnti-Up3a antibodyAnti-Uroplakin Iii antibodyAnti-Upiii antibodyAnti-UPK3A antibodyAnti-UPK3 antibody |
Information sourced from Uniprot.org