Anti-UNC45B antibody (STJA0004578)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human UNC45B
General Information
| Short Description | Rabbit polyclonal antibody anti-Protein Unc-45 Homolog B is suitable for use in Western Blot and ELISA research applications. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | UNC45B |
| Gene ID | 146862 |
| Uniprot ID | UN45B_HUMAN |
| Immunogen | Fusion protein of human UNC45B |
Additional Info
| Tissue Specificity | Expressed in eye lens tissues. Expressed in muscle (at protein level). |
| Function | Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. |
| Protein Name | Protein Unc-45 Homolog BUnc-45bSmunc45 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineA BandPerinuclear RegionCytosolExpressed At The Z Line And In The Perinuclear Region Of MyofibrilsTranslocates To The A Band In Response To Stress Conditions And Fibril Damage |
| Alternative Antibody Names | Anti-Protein Unc-45 Homolog B antibodyAnti-Unc-45b antibodyAnti-Smunc45 antibodyAnti-UNC45B antibodyAnti-CMYA4 antibodyAnti-UNC45 antibody |
Information sourced from Uniprot.org