| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-UNC45B (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
UNC45B |
| Gene ID: |
146862 |
| Uniprot ID: |
UN45B_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_775259.1; NP_001028748.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms (NP_775259.1and NP_001028748.1). |
| Immunogen Sequence: |
RSDKLRQKIFKER |
| Function | Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. |
| Protein Name | Protein Unc-45 Homolog BUnc-45bSmunc45 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineA BandPerinuclear RegionCytosolExpressed At The Z Line And In The Perinuclear Region Of MyofibrilsTranslocates To The A Band In Response To Stress Conditions And Fibril Damage |
| Alternative Antibody Names | Anti-Protein Unc-45 Homolog B antibodyAnti-Unc-45b antibodyAnti-Smunc45 antibodyAnti-UNC45B antibodyAnti-CMYA4 antibodyAnti-UNC45 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
