Anti-UNC45A antibody (259-309 aa) (STJ194584)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human UN45A at the amino acid range 259-309
General Information
| Short Description | Rabbit polyclonal anti-Protein unc-45 homolog A (259-309 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UNC45A |
| Gene ID | 55898 |
| Uniprot ID | UN45A_HUMAN |
| Immunogen | Synthesized peptide derived from the human UN45A at the amino acid range 259-309 |
| Immunogen Region | 259-309 aa |
| Specificity | This antibody detects endogenous levels of UN45A at Human/Mouse/Rat |
Additional Info
| Function | Acts as a co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen. |
| Protein Name | Protein Unc-45 Homolog AUnc-45aGcunc-45Smooth Muscle Cell-Associated Protein 1Smap-1 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusPredominant In The Perinuclear RegionLittle Protein In The Nucleus |
| Alternative Antibody Names | Anti-Protein Unc-45 Homolog A antibodyAnti-Unc-45a antibodyAnti-Gcunc-45 antibodyAnti-Smooth Muscle Cell-Associated Protein 1 antibodyAnti-Smap-1 antibodyAnti-UNC45A antibodyAnti-SMAP1 antibody |
Information sourced from Uniprot.org