Anti-UMPS antibody (100-260) (STJ115216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UMPS (100-260) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UMPS |
| Gene ID | 7372 |
| Uniprot ID | UMPS_HUMAN |
| Immunogen Region | 100-260 |
| Immunogen Sequence | TKDYGTKRLVEGTINPGETC LIIEDVVTSGSSVLETVEVL QKEGLKVTDAIVLLDREQGG KDKLQAHGIRLHSVCTLSKM LEILEQQKKVDAETVGRVKR FIQENVFVAANHNGSPLSIK EAPKELSFGARAELPRIHPV ASKLLRLMQKKETNLCLSAD V |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1). |
Additional Info
| Function | Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP). |
| Protein Name | Uridine 5'-Monophosphate SynthaseUmp Synthase Includes - Orotate PhosphoribosyltransferaseOprtOprtase - Orotidine 5'-Phosphate DecarboxylaseOdcOmpdOmpdecase |
| Database Links | Reactome: R-HSA-500753 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Uridine 5'-Monophosphate Synthase antibodyAnti-Ump Synthase Includes - Orotate Phosphoribosyltransferase antibodyAnti-Oprt antibodyAnti-Oprtase - Orotidine 5'-Phosphate Decarboxylase antibodyAnti-Odc antibodyAnti-Ompd antibodyAnti-Ompdecase antibodyAnti-UMPS antibodyAnti-OK antibodyAnti-SW-cl.21 antibody |
Information sourced from Uniprot.org