Anti-UEV2V2/MMS2 antibody (N-Term) (STJ70164)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-UEV2V2/MMS2 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 20kDa band seen in human brain lysate. Recommended for use at 0.2-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2V2 |
| Gene ID | 7336 |
| Uniprot ID | UB2V2_HUMAN |
| Accession Number | NP_003341.1; NP_954673.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | AVSTGVKVPRNF |
| Specificity | This antibody is also expected to recognize the readthrough transcript product KUA-UEV (NP_954673.1, GeneID 387522). Also cross-reactivity is expected with UEV2V1 (GeneID 7335). |
Additional Info
| Function | Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 Variant 2Ddvit 1Enterocyte Differentiation-Associated Factor 1Edaf-1Enterocyte Differentiation-Promoting Factor 1Edpf-1Mms2 HomologVitamin D3-Inducible Protein |
| Database Links | Reactome: R-HSA-5693565Reactome: R-HSA-5693571Reactome: R-HSA-5693607Reactome: R-HSA-5696395Reactome: R-HSA-69473Reactome: R-HSA-8866654Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 Variant 2 antibodyAnti-Ddvit 1 antibodyAnti-Enterocyte Differentiation-Associated Factor 1 antibodyAnti-Edaf-1 antibodyAnti-Enterocyte Differentiation-Promoting Factor 1 antibodyAnti-Edpf-1 antibodyAnti-Mms2 Homolog antibodyAnti-Vitamin D3-Inducible Protein antibodyAnti-UBE2V2 antibodyAnti-MMS2 antibodyAnti-UEV2 antibody |
Information sourced from Uniprot.org