Anti-UCHL5 antibody [R03-9C1] (STJA0034975)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human UCH37
General Information
| Short Description | Rabbit monoclonal anti-UCHL5 for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-9C1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | UCHL5 |
| Gene ID | 51377 |
| Uniprot ID | UCHL5_HUMAN |
| Immunogen | A synthetic peptide of human UCH37 |
Additional Info
| Function | Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex.however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L5Uch-L5Ubiquitin C-Terminal Hydrolase Uch37Ubiquitin Thioesterase L5 |
| Database Links | Reactome: R-HSA-2173788Reactome: R-HSA-5689603 |
| Cellular Localisation | CytoplasmNucleusAssociates With The Proteasome 19s Subunit In The CytoplasmAssociates With The Ino80 Complex In The Nucleus |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L5 antibodyAnti-Uch-L5 antibodyAnti-Ubiquitin C-Terminal Hydrolase Uch37 antibodyAnti-Ubiquitin Thioesterase L5 antibodyAnti-UCHL5 antibodyAnti-UCH37 antibodyAnti-AD-019 antibodyAnti-CGI-70 antibody |
Information sourced from Uniprot.org