Anti-UBE4A antibody (797-1066) (STJ26241)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UBE4A (797-1066) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE4A |
| Gene ID | 9354 |
| Uniprot ID | UBE4A_HUMAN |
| Immunogen Region | 797-1066 |
| Immunogen Sequence | FLLDEAIQYLSKIKIQQIEK DRGEWDSLTPEARREKEAGL QMFGQLARFHNIMSNETIGT LAFLTSEIKSLFVHPFLAER IISMLNYFLQHLVGPKMGAL KVKDFSEFDFKPQQLVSDIC TIYLNLGDEENFCATVPKDG RSYSPTLFAQTVRVLKKINK PGNMIMAFSNLAERIKSLAD LQQQEEETYADACDEFLDPI MSTLMCDPVVLPSSRVTVDR STIARHLLSDQTDPFNRSP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A (NP_001191006.1). |
Additional Info
| Function | Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates. |
| Protein Name | Ubiquitin Conjugation Factor E4 ARing-Type E3 Ubiquitin Transferase E4 A |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin Conjugation Factor E4 A antibodyAnti-Ring-Type E3 Ubiquitin Transferase E4 A antibodyAnti-UBE4A antibodyAnti-KIAA0126 antibody |
Information sourced from Uniprot.org