Anti-UBE2T antibody (121-170 aa) (STJ96165)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human UBE2T at the amino acid range 121-170
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin-conjugating enzyme E2 T (121-170 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2T |
| Gene ID | 29089 |
| Uniprot ID | UBE2T_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human UBE2T at the amino acid range 121-170 |
| Immunogen Region | 121-170 aa |
| Specificity | UBE2T Polyclonal Antibody detects endogenous levels of UBE2T protein. |
Additional Info
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 TCell Proliferation-Inducing Gene 50 ProteinE2 Ubiquitin-Conjugating Enzyme TUbiquitin Carrier Protein TUbiquitin-Protein Ligase T |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-8866652 |
| Cellular Localisation | NucleusAccumulates To Chromatin |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 T antibodyAnti-Cell Proliferation-Inducing Gene 50 Protein antibodyAnti-E2 Ubiquitin-Conjugating Enzyme T antibodyAnti-Ubiquitin Carrier Protein T antibodyAnti-Ubiquitin-Protein Ligase T antibodyAnti-UBE2T antibodyAnti-HSPC150 antibodyAnti-PIG50 antibody |
Information sourced from Uniprot.org