| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBE2E1 |
| Gene ID: | 7324 |
| Uniprot ID: | UB2E1_HUMAN |
| Immunogen Region: | 1-50 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-50 of human UBE2E1 (NP_003332.1). |
| Immunogen Sequence: | MSDDDSRASTSSSSSSSSNQ QTEKETNTPKKKESKVSMSK NSKLLSTSAK |
| Post Translational Modifications | ISGylation suppresses ubiquitin E2 enzyme activity. Autoubiquitinated in vitro. |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. Catalyzes monoubiquitination of other proteins in both an E3-dependent and E3-independent manner. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 E1(E3-Independent E2 Ubiquitin-Conjugating Enzyme E1E2 Ubiquitin-Conjugating Enzyme E1Ubch6Ubiquitin Carrier Protein E1Ubiquitin-Protein Ligase E1 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-141430Reactome: R-HSA-174048Reactome: R-HSA-174084Reactome: R-HSA-174154Reactome: R-HSA-174178Reactome: R-HSA-174184Reactome: R-HSA-176407Reactome: R-HSA-176408Reactome: R-HSA-176409Reactome: R-HSA-176412Reactome: R-HSA-179409Reactome: R-HSA-2467813Reactome: R-HSA-2559582Reactome: R-HSA-68867Reactome: R-HSA-69017Reactome: R-HSA-8853884Reactome: R-HSA-8866652Reactome: R-HSA-8866654Reactome: R-HSA-9687136Reactome: R-HSA-983168 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 E1 antibodyAnti-(E3-Independent E2 Ubiquitin-Conjugating Enzyme E1 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme E1 antibodyAnti-Ubch6 antibodyAnti-Ubiquitin Carrier Protein E1 antibodyAnti-Ubiquitin-Protein Ligase E1 antibodyAnti-UBE2E1 antibodyAnti-UBCH6 antibody |
Information sourced from Uniprot.org
