| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin-associated and SH3 domain-containing protein A (311-360 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UBASH3A |
| Gene ID: |
53347 |
| Uniprot ID: |
UBS3A_HUMAN |
| Immunogen Region: |
311-360 aa |
| Specificity: |
TULA Polyclonal Antibody detects endogenous levels of TULA protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human UBASH3A at the amino acid range 311-360 |
| Function | Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. |
| Protein Name | Ubiquitin-Associated And Sh3 Domain-Containing Protein ACbl-Interacting Protein 4Clip4Suppressor Of T-Cell Receptor Signaling 2Sts-2T-Cell Ubiquitin Ligand 1Tula-1 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin-Associated And Sh3 Domain-Containing Protein A antibodyAnti-Cbl-Interacting Protein 4 antibodyAnti-Clip4 antibodyAnti-Suppressor Of T-Cell Receptor Signaling 2 antibodyAnti-Sts-2 antibodyAnti-T-Cell Ubiquitin Ligand 1 antibodyAnti-Tula-1 antibodyAnti-UBASH3A antibodyAnti-STS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
