Anti-UBAC2 antibody (220-310) (STJ118422)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UBAC2 (220-310) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBAC2 |
| Gene ID | 337867 |
| Uniprot ID | UBAC2_HUMAN |
| Immunogen Region | 220-310 |
| Immunogen Sequence | PIFSSSEPTSEARIGMGATL DIQRQQRMELLDRQLMFSQF AQGRRQRQQQGGMINWNRLF PPLRQRQNVNYQGGRQSEPA APPLEVSEEQV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human UBAC2 (NP_001137544.1). |
Additional Info
| Function | Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. |
| Protein Name | Ubiquitin-Associated Domain-Containing Protein 2Uba Domain-Containing Protein 2Phosphoglycerate Dehydrogenase-Like Protein 1 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ubiquitin-Associated Domain-Containing Protein 2 antibodyAnti-Uba Domain-Containing Protein 2 antibodyAnti-Phosphoglycerate Dehydrogenase-Like Protein 1 antibodyAnti-UBAC2 antibodyAnti-PHGDHL1 antibodyAnti-PSEC0110 antibody |
Information sourced from Uniprot.org