• Western blot analysis of lysates from 293 and HUVEC cells, using UBAC1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HT-29 cells using UBAC1 antibody.
  • Western blot analysis of various cells using GBDR1 Polyclonal Antibody diluted at 1：500

Anti-UBAC1 antibody (91-140 aa) (STJ93231)

SKU:
STJ93231

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ubiquitin-associated domain-containing protein 1 (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UBAC1
Gene ID: 10422
Uniprot ID: UBAC1_HUMAN
Immunogen Region: 91-140 aa
Specificity: GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human UBAC1 at the amino acid range 91-140
Function Non-catalytic component of the KPC complex, a E3 ubiquitin-protein ligase complex that mediates polyubiquitination of target proteins, such as CDKN1B and NFKB1. The KPC complex catalyzes polyubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. The KPC complex also acts as a key regulator of the NF-kappa-B signaling by promoting maturation of the NFKB1 component of NF-kappa-B by catalyzing ubiquitination of the NFKB1 p105 precursor. Within the KPC complex, UBAC1 acts as an adapter that promotes the transfer of target proteins that have been polyubiquitinated by RNF123/KPC1 to the 26S proteasome.
Protein Name Ubiquitin-Associated Domain-Containing Protein 1
Uba Domain-Containing Protein 1
Glialblastoma Cell Differentiation-Related Protein 1
Kip1 Ubiquitination-Promoting Complex Protein 2
Database Links Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Ubiquitin-Associated Domain-Containing Protein 1 antibody
Anti-Uba Domain-Containing Protein 1 antibody
Anti-Glialblastoma Cell Differentiation-Related Protein 1 antibody
Anti-Kip1 Ubiquitination-Promoting Complex Protein 2 antibody
Anti-UBAC1 antibody
Anti-GBDR1 antibody
Anti-KPC2 antibody
Anti-UBADC1 antibody

Information sourced from Uniprot.org

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