Anti-UBAC1 antibody (91-140 aa) (STJ93231)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human UBAC1 at the amino acid range 91-140
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin-associated domain-containing protein 1 (91-140 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBAC1 |
| Gene ID | 10422 |
| Uniprot ID | UBAC1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human UBAC1 at the amino acid range 91-140 |
| Immunogen Region | 91-140 aa |
| Specificity | GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein. |
Additional Info
| Function | Non-catalytic component of the KPC complex, a E3 ubiquitin-protein ligase complex that mediates polyubiquitination of target proteins, such as CDKN1B and NFKB1. The KPC complex catalyzes polyubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. The KPC complex also acts as a key regulator of the NF-kappa-B signaling by promoting maturation of the NFKB1 component of NF-kappa-B by catalyzing ubiquitination of the NFKB1 p105 precursor. Within the KPC complex, UBAC1 acts as an adapter that promotes the transfer of target proteins that have been polyubiquitinated by RNF123/KPC1 to the 26S proteasome. |
| Protein Name | Ubiquitin-Associated Domain-Containing Protein 1Uba Domain-Containing Protein 1Glialblastoma Cell Differentiation-Related Protein 1Kip1 Ubiquitination-Promoting Complex Protein 2 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin-Associated Domain-Containing Protein 1 antibodyAnti-Uba Domain-Containing Protein 1 antibodyAnti-Glialblastoma Cell Differentiation-Related Protein 1 antibodyAnti-Kip1 Ubiquitination-Promoting Complex Protein 2 antibodyAnti-UBAC1 antibodyAnti-GBDR1 antibodyAnti-KPC2 antibodyAnti-UBADC1 antibody |
Information sourced from Uniprot.org