Anti-TYMS antibody (1-313) (STJ112471)

Name: Anti-TYMS antibody (1-313) (STJ112471)
SKU: STJ112471
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⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ112471

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Short Description	Rabbit polyclonal TYMS (1-313) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	TYMS
Gene ID	7298
Uniprot ID	TYSY_HUMAN
Immunogen Region	1-313
Immunogen Sequence	MPVAGSELPRRPLPPAAQER DAEPRPPHGELQYLGQIQHI LRCGVRKDDRTGTGTLSVFG MQARYSLRDEFPLLTTKRVF WKGVLEELLWFIKGSTNAKE LSSKGVKIWDANGSRDFLDS LGFSTREEGDLGPVYGFQWR HFGAEYRDMESDYSGQGVDQ LQRVIDTIKTNPDDRRIIMC AWNPRDLPLMALPPCHALCQ FYVVNSELSCQLYQRSGDMG LGVPFNIASYALLTYMIAH
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human TYMS (NP_001062.1).

Function	Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Protein Name	Thymidylate Synthase Ts Tsase
Database Links	Reactome: R-HSA-499943 Reactome: R-HSA-69205
Cellular Localisation	Nucleus Cytoplasm Mitochondrion Mitochondrion Matrix Mitochondrion Inner Membrane
Alternative Antibody Names	Anti-Thymidylate Synthase antibody Anti-Ts antibody Anti-Tsase antibody Anti-TYMS antibody Anti-TS antibody Anti-OK antibody Anti-SW-cl.29 antibody

Information sourced from Uniprot.org