Anti-TXNRD2 antibody [3F2-E12-F10] (STJ99154)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human TXNRD2 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Thioredoxin reductase 2, mitochondrial for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3F2-E12-F10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TXNRD2 |
| Gene ID | 10587 |
| Uniprot ID | TRXR2_HUMAN |
| Immunogen | Purified recombinant human TXNRD2 protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of TXNRD2 and does not cross-react with related proteins. |
Additional Info
| Function | Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. |
| Protein Name | Thioredoxin Reductase 2 - MitochondrialSelenoprotein ZSelzTr-BetaThioredoxin Reductase Tr3 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Thioredoxin Reductase 2 - Mitochondrial antibodyAnti-Selenoprotein Z antibodyAnti-Selz antibodyAnti-Tr-Beta antibodyAnti-Thioredoxin Reductase Tr3 antibodyAnti-TXNRD2 antibodyAnti-KIAA1652 antibodyAnti-TRXR2 antibody |
Information sourced from Uniprot.org