• Western blot analysis of extracts of various cell lines, using TXNL4A antibody (STJ112177) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TXNL4A antibody (1-142) (STJ112177)

SKU:
STJ112177

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TXNL4A (1-142) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TXNL4A
Gene ID: 10907
Uniprot ID: TXN4A_HUMAN
Immunogen Region: 1-142
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1).
Immunogen Sequence: MSYMLPHLHNGWQVDQAILS EEDRVVVIRFGHDWDPTCMK MDEVLYSIAEKVKNFAVIYL VDITEVPDFNKMYELYDPCT VMFFFRNKHIMIDLGTGNNN KINWAMEDKQEMVDIIETVY RGARKGRGLVVSPKDYSTKY RY
Post Translational Modifications The disulfide bond seen in structures determined by X-ray crystallography and NMR is not essential for protein folding and function.
Function Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Protein Name Thioredoxin-Like Protein 4a
Dim1 Protein Homolog
Spliceosomal U5 Snrnp-Specific 15 Kda Protein
Thioredoxin-Like U5 Snrnp Protein U5-15kd
Database Links Reactome: R-HSA-72163
Reactome: R-HSA-72165
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Thioredoxin-Like Protein 4a antibody
Anti-Dim1 Protein Homolog antibody
Anti-Spliceosomal U5 Snrnp-Specific 15 Kda Protein antibody
Anti-Thioredoxin-Like U5 Snrnp Protein U5-15kd antibody
Anti-TXNL4A antibody
Anti-DIM1 antibody
Anti-TXNL4 antibody

Information sourced from Uniprot.org

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