Anti-TXNDC3 antibody (Internal) (STJ71570)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TXNDC3 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments in Human Testis lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NME8 |
| Gene ID | 51314 |
| Uniprot ID | TXND3_HUMAN |
| Accession Number | NP_057700.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | TEPQTDTEPNERSE |
Additional Info
| Function | Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. In vitro, it has neither nucleoside diphosphate kinase (NDPK) activity nor reducing activity on disulfide bonds. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair. |
| Protein Name | Thioredoxin Domain-Containing Protein 33'-5' Exonuclease Nme8Nm23-H8Nme/Nm23 Family Member 8Spermatid-Specific Thioredoxin-2Sptrx-2 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Thioredoxin Domain-Containing Protein 3 antibodyAnti-3'-5' Exonuclease Nme8 antibodyAnti-Nm23-H8 antibodyAnti-Nme/Nm23 Family Member 8 antibodyAnti-Spermatid-Specific Thioredoxin-2 antibodyAnti-Sptrx-2 antibodyAnti-NME8 antibodyAnti-SPTRX2 antibodyAnti-TXNDC3 antibody |
Information sourced from Uniprot.org