| Tissue Specificity | Ubiquitously expressed (at protein level). |
| Post Translational Modifications | In vitro, phosphorylated by PRKCZ, CK2 and SRC. |
| Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia. |
| Protein Name | Twinfilin-2A6-Related ProteinHa6rpProtein Tyrosine Kinase 9-LikeTwinfilin-1-Like Protein |
| Database Links | Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonPerinuclear RegionCell ProjectionStereociliumPerinuclear And G-Actin-Rich Cortical Actin Structure Sublocalization |
| Alternative Antibody Names | Anti-Twinfilin-2 antibodyAnti-A6-Related Protein antibodyAnti-Ha6rp antibodyAnti-Protein Tyrosine Kinase 9-Like antibodyAnti-Twinfilin-1-Like Protein antibodyAnti-TWF2 antibodyAnti-PTK9L antibodyAnti-MSTP011 antibody |
Information sourced from Uniprot.org
