Anti-TWF1 antibody (101-350) (STJ117502)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TWF1 (101-350) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TWF1 |
| Gene ID | 5756 |
| Uniprot ID | TWF1_HUMAN |
| Immunogen Region | 101-350 |
| Immunogen Sequence | YAATRATLKKEFGGGHIKDE VFGTVKEDVSLHGYKKYLLS QSSPAPLTAAEEELRQIKIN EVQTDVGVDTKHQTLQGVAF PISREAFQALEKLNNRQLNY VQLEIDIKNEIIILANTTNT ELKDLPKRIPKDSARYHFFL YKHSHEGDYLESIVFIYSMP GYTCSIRERMLYSSCKSRLL EIVERQLQMDVIRKIEIDNG DELTADFLYEEVHPKQHAHK QSFAKPKGPAGKRGIRRLI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 101-350 of human TWF1 (NP_002813.3). |
Additional Info
| Tissue Specificity | Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. |
| Post Translational Modifications | Phosphorylated on serine and threonine residues. |
| Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. |
| Protein Name | Twinfilin-1Protein A6Protein Tyrosine Kinase 9 |
| Database Links | Reactome: R-HSA-9013418Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonDiffuse Cytoplasmic Localization With Perinuclear And G-Actin-Rich Cortical Actin Structures SublocalizationAlso Found At Membrane Ruffles And Cell-Cell Contacts |
| Alternative Antibody Names | Anti-Twinfilin-1 antibodyAnti-Protein A6 antibodyAnti-Protein Tyrosine Kinase 9 antibodyAnti-TWF1 antibodyAnti-PTK9 antibody |
Information sourced from Uniprot.org