Anti-TUSC2 antibody (1-110) (STJ29155)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TUSC2 (1-110) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TUSC2 |
| Gene ID | 11334 |
| Uniprot ID | TUSC2_HUMAN |
| Immunogen Region | 1-110 |
| Immunogen Sequence | MGASGSKARGLWPFASAAGG GGSEAAGAEQALVRPRGRAV PPFVFTRRGSMFYDEDGDLA HEFYEETIVTKNGQKRAKLR RVHKNLIPQGIVKLDHPRIH VDFPVILYEV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1). |
Additional Info
| Tissue Specificity | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |
| Post Translational Modifications | Myristoylation is required for tumor suppressor activity. |
| Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
| Protein Name | Tumor Suppressor Candidate 2Fusion 1 ProteinFus-1 ProteinPdgfa-Associated Protein 2 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tumor Suppressor Candidate 2 antibodyAnti-Fusion 1 Protein antibodyAnti-Fus-1 Protein antibodyAnti-Pdgfa-Associated Protein 2 antibodyAnti-TUSC2 antibodyAnti-C3orf11 antibodyAnti-FUS1 antibodyAnti-LGCC antibodyAnti-PDAP2 antibody |
Information sourced from Uniprot.org